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. Author manuscript; available in PMC: 2013 Oct 28.
Published in final edited form as: Mol Psychiatry. 2008 Jan 15;13(4):10.1038/sj.mp.4002147. doi: 10.1038/sj.mp.4002147

Figure 1.

Figure 1

Distribution of the negative log10 P-values of the association of genotype and allele frequency with heroin addiction of each variant across the genome. The negative log10 P-values for the point-wise significance of the genotype frequency (pink squares) and allele frequency (blue diamonds) association analyses with heroin addiction (ordinate) are plotted versus their location on their respective chromosome in the genome in Mb (1 million bases) (abscissa). The two most significantly associated variants, with q-values of less than 0.2 by experiment-wise association of genotype or allele frequency with heroin addiction were rs965972 and rs1986513, which are located on chromosomes 1 and 4, respectively, and are indicated with ←.