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. Author manuscript; available in PMC: 2013 Oct 28.
Published in final edited form as: Circ Res. 2012 Aug 8;111(8):10.1161/CIRCRESAHA.112.270314. doi: 10.1161/CIRCRESAHA.112.270314

Figure 1. Atherogenicity of TGRL varies with postprandial particle composition.

Figure 1

TGRLs were analyzed for their composition using a clinical chemistry analyzer and each component was normalized to ApoB concentration in the sample to obtain a per particle density. TGRLs (10 mg/dl ApoB) were characterized for their atherogenicity, defined by the ability to positively (pro) or negatively (anti) modulate TNFα (0.3 ng/ml)-induced VCAM-1 expression in HAEC at 4 hr. Correlation of particle density for (A) TG, (B) ApoCIII, (C) ApoE, and (D) Cholesterol with the % change in VCAM-1 expression from TNFα. (E-H) Particle compositions for the same samples categorized by their ability to positively or negatively modulate VCAM-1 expression. (*P<0.05, **P<0.01, ***P<0.001 from paired TNFα; n=22–28).