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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Acad Radiol. 2013 Sep;20(9):10.1016/j.acra.2013.04.013. doi: 10.1016/j.acra.2013.04.013

Table 3.

Fisher probability analysis of the correlation of response to treatment at six months with the pretreatment tumor PME/NTP and IPI using the maximum of the Youden index for comparative purposes (left and middle truth tables, respectively) and the pretreatment tumor PME/NTP using the cutoff for maximum sensitivity (right truth table)

treatment response treatment response treatment response
PME/NTP CR1 PR total IPI CR PR total PME/NTP CR PR total
≤ 1.92 12 1 13 ≤ 2.0 11 3 14 ≤ 2.2 13 2 15
> 1.92 1 6 7 > 2.0 2 4 6 > 2.2 0 5 5
total 13 7 20 total 13 7 20 total 13 7 20
accuracy = 0.90 accuracy = 0.75 accuracy = 0.90
prevalence = 0.65 prevalence = 0.65 prevalence = 0.65
sensitivity = 0.92 sensitivity = 0.85 sensitivity = 1.00
specificity = 0.86 specificity = 0.57 specificity = 0.71
false negative rate = 0.08 false negative rate = 0.15 false negative rate = 0.00
false positive rate = 0.14 false positive rate = 0.43 false positive rate = 0.29
positive predictive value = 0.92 positive predictive value = 0.79 positive predictive value = 0.87
negative predictive value = 0.86 negative predictive value = 0.86 negative predictive value = 1.00
p < 0.001 p < 0.07 p < 0.001
1

Abbreviations: CR, complete response; PR, partial response