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Serum ALP and Skeletal Traits of B6 Background and B6.D2.Ch4 Congenic Mice
| B6 background (n=40; 20F/20M) | B6.D2.Ch4 congenic (n=39; 20F/19M) | p value | |
|---|---|---|---|
| Serum ALP activity (U/L) | 60±5 | 142±12 | <0.0001 |
| Femoral bone traits | |||
| BMD (mg/cm2) | 54.6±1.0 | 58.8±0.7 | <0.005 |
| Cortical thickness (µm) | 158±2 | 169±1 | <0.0005 |
| Ultimate failure load (N) | 14.5 ±0.5 | 17.3 ±0.8 | <0.01 |
ALP=alkaline phosphatase; BMD= bone mineral density; F = female; M=male.
