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. Author manuscript; available in PMC: 2014 Sep 23.
Published in final edited form as: Vaccine. 2013 Aug 1;31(41):10.1016/j.vaccine.2013.07.030. doi: 10.1016/j.vaccine.2013.07.030

Figure 2. Majority of PPS-specific B cells express CD27 and IgM post-immunization with PPV.

Figure 2

Lymphocyte enriched peripheral blood samples were stained with immunofluorescent PPS and antibodies to be evaluated by flow cytometry. The phenotype distribution of CD27 and IgM on CD19+ B cells was compared for day-0, day-7, and day-30 for PPS14-(A) and PPS23F- (B) selected cells. The phenotypic distribution of CD27 and IgM was compared on day-7 for unselected, PPS14- and PPS23F- selected cells (C). Mean values with SEM shown. In each sample, 100,000 events were recorded. *p < 0.05, **p < 0.01, ***p<0.001.