Figure 1.

miR-26b expression is upregulated in AD. A, A table summarizes information about the samples used in this study. B, Multiplex miRNA expression analyses were performed on samples from temporal cortex of Braak III (n = 6) and control brains (n = 6). C, Expression of miR-26b (top) and miR-26a (bottom) was tested in control, Braak III, and Braak VI (n = 8–10 per condition) specimens by singleplex qRT-PCR, and relative levels calculated as 2^−ΔCt. Uniformly expressed miR-99a was used for normalization. Data represent mean ± SEM with Mann–Whitney test.