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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Health Phys. 2013 Dec;105(6):10.1097/HP.0b013e31829cf221. doi: 10.1097/HP.0b013e31829cf221

Table 1. Comparison of biodosimetry method properties.

Method Dose Range
(Gy)
Time before sample
can be taken
Time to dose
estimate
Time period when
assay will give
results
Dicentric Chromosome 0.1–5 Immediately 55 + h 3–6+ mo
Assay 0.5–5 (triage) 52+ h
Cytokinesis Block
Micronucleus
0.3–5 Immediately 3+ d 6 mo –1 y
γ–H2AX Immediately 24–48 h
Microscope 0.5–5 4–6 h
FACS 0.5–10 2 h
Lymphocyte Depletion
Kinetics Assay
0.5/1–10 Immediately for
baseline, time needed
for depletion to occur
<1 h per test.
Serial testing
requires 8-48 h.
12 h– 7 d
Premature Chromosome Condensation 0.2–20 Immediately CHO fusion: 2–3 h
Chemical
stimulation: 51 h
At least 1 wk, likely
6+ mo
Gene Expression 0.1–5 Immediately,
depending on when
gene is upregulated
9–36 h Through 48–72 h
EPR (tooth) 1–30 Immediately 5–25 min Lifetime and longer