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. Author manuscript; available in PMC: 2014 Dec 1.
Published in final edited form as: Health Phys. 2013 Dec;105(6):10.1097/HP.0b013e31829cf221. doi: 10.1097/HP.0b013e31829cf221

Table 3. Important Characteristics for biodosimetry methods to be used after an IND incident.

Characteristic Reason
Simple sample collection method Requires fewer specially trained personnel
Field-readiness Samples can be run on site, little sample
preparation required
Short time to result Results can be used to guide treatment more
quickly
High-capacity A large number of samples can be run on one
instrument
Time to result Medical care can begin earlier with a fast time
to result
Dual-utility Method in routine use, return on investment,
personnel will be trained and used to
performing test
Method standardization Ease of comparing results across laboratories,
systematic training
Specificity for radiation Low background signal, not affected by
confounders such as inflammation or infection
Low inter-individual variation Baseline would not need to be determined for
each segment of the population (e.g. age,
gender)
Low intra-individual variation Decreased need for repeated tests, test not
confounded by infection or other medical
treatments
Low uncertainty in the result Decreased need for repeated tests
Stable output signal Increases the amount of time the assay can be
used
Inexpensive sample processing Number of tests required will be large and cost
will add up quickly