Table 1.
Group demographics.
| Lean (n = 32) |
Obese (n = 63) | P-value | |
|---|---|---|---|
| Age (years) | 17.3 ± 1.6 (14.3–20.1) | 17.5 ± 1.8 (14.3–21.6) |
.79 |
| Sex (% female) | 59.2 | 61.9 | .81 |
| Grade | 11.8 ± 1.9 (9.0–16.0) |
11.6 ± 1.7 (8.1–16.1) |
.57 |
| Socioeconomic status | 2.6 ± 1.4 | 2.1 ± 1.2 | .19 |
| BMI (kg/m2) | 21.1 ± 2 (17.44–24.9) |
37.7 ± 5.9 (27.8–49.8) |
<.001 |
| BMI percentile | 50.9 ± 22.5 (9.0–79.9) | 98.2 ± 1.3 (95.2–99.9) |
<.001 |
| Waist circumference (cm) | 75.3 ± 6.2 (66.0–88.0) |
112.9 ± 13.4 (88.0–147.0) |
<.001 |
| Waist:height | 0.4 ± 0.0 (0.39–0.5) |
0.7 ± 0.1 (0.51–0.82) |
<.001 |
| Glucose (mg/dL) | 74.6 ± 6.9 (62.0–89.0) |
97.4 ± 55.2 (62.0–343.0) |
.004 |
| Insulin (IU/mL) | 7.1 ± 3.3 (2.0–15.2) |
22.8 ± 19.2 (2.2–123.0) |
<.001 |
| HOMA-IR | 1.3 ± 0.6 (0.36–2.5) |
5.5 ± 5.5 (0.52–33.4) |
<.001 |
| Hemoglobin A1C (%) | 5.2 ± 0.4 (4.6–6.8) |
6.2 ± 2.1 (4.7–14.6) |
.001 |
| Triglycerides | 67.7 ± 45.9 (25.0–165.0) |
93.9 ± 45.9 (24.0–228.0) |
.002 |
| Total cholesterol (mg/dL) | 157.3 ± 29.9 (100.0–212.0) |
166.2 ± 30.3 (113.0–263.0) |
.18 |
| HDL (mg/dL) | 55.4 ± 11.3 (35.0–80.0) |
42.3 ± 9.4 (26.0–66.0) |
<.001 |
| LDL (mg/dL) | 88.5 ± 24.9 (45.0–139.0) |
103.4 ± 25.7 (59.0–164.0) |
.01 |
| CRP (mg/L) | 0.8 ± 1.7 (0.05–9.30) |
3.2 ± 2.4 (0.3–9.90) |
<.001 |
| Fibrinogen (mg/dL) | 285.8 ± 42.0 (220.0–376.0) |
349.8 ± 77.7 (189.0–565.0) |
<.001 |
| Systolic BP (mmHg) | 100.2 ± 8.1 (88–118) |
116.0 ± 13.1 (96–160) |
<.001 |
| Diastolic BP (mmHg) | 61.8 ± 5.6 (50–80) |
68.1 ± 9.0 (52–100) |
<.001 |
Data are presented as mean ± SD (min–max).