Table 3. Pairwise interlocus linkage disequilibrium and recombination analysis of concatenated multilocus sequences from various subtypes of Cryptosporidium hominis*.

Population	No. samples	No. segregating sites analyzed	No. pairwise comparisons	No. significant pairwise comparisons†	Zns	|D'|	LD	Estimate of R/gene	Minimum no. recombination events
Including gp60‡
All	53	362	47,895	25,904 (8,714)	0.2711	Y = 0.9289 – 0.0299X	Incomplete	5.0	33
IaA13R8(7)	10	20	190	0	0.7581	Y = 1.0000 + 0.0000X	Complete	0.001	0
IbA10G2	26	31	465	160 (140)	0.3660	Y = 0.9342 + 0.0001X	Incomplete	0.3	4
IdA10	6	14	91	0	1.0000	Y = 1.0000 + 0.0000X	Complete	0.001	0
IdA20	5	3	3	0	0.3750	Y = 1.0000 + 0.0000X	Complete	0.001	0
IeA11G3T3	6	19	171	0	1.0000	Y = 1.0000 + 0.0000X	Complete	0.001	0
Excluding gp60§
All	53	65	2080	921 (333)	0.2184	Y = 0.7886 + 0.0051X	Incomplete	1.8	6
IaA13R8(7)	10	20	190	0	0.7581	Y = 1.0000 + 0.0000X	Complete	0.001	0
IbA10G2	26	31	465	160 (140)	0.3660	Y = 0.9302 + 0.0010X	Incomplete	0.3	4
IdA10	6	14	91	0	1.0000	Y = 1.0000 + 0.0000X	Complete	0.001	0
IdA20	5	3	3	0	0.3750	Y = 1.0000 + 0.0000X	Complete	0.001	0
IeA11G3T3	6	19	171	0	1.0000	Y = 1.0000 + 0.0000X	Complete	0.001	0

*Zns, interlocus genetic association; |D'|, linkage disequilibrium (LD) value, where Y is LD value and X is nucleotide distance in kilobases; gp 60, 60-kDa glycoprotein gene.
†By Fisher exact test (after Bonferroni correction).
‡Based on concatenated multilocus gene sequence of all loci (15,717 bp). 
§Based on concatenated multilocus gene sequence of all loci excluding gp60 (14,768 bp).