Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2013 Oct 29;7:175. doi: 10.3389/fncir.2013.00175

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2013 Sivaramakrishnan, Sanchez and Grimsley.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) or licensor are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Criterion for a complete separation of mono- and polysynaptic influences on firing rate in vivo. (A) Achievement of steady state RIFs in HiDi. Raster plots in control (top) and after the second (middle) and fifth (bottom) pulse of 2.5 HiDi indicate gradually greater decrease in firing with successive HiDi pulses. (B) Top: change in the RIF with repeated HiDi application. In this cell, four HiDi pulses (each pulse was 500 ms, 8 psi) were required to reach a steady-state RIF. RIFs measured after the fourth, fifth and sixth HiDi pulses are superimposed. Bottom: recovery from HiDi (blue trace) ~6 min after the application was stopped.