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A, Nampt mRNA was measured in C57BL/6J mouse quadriceps muscle 2, 4 and 8 h after AICAR injection (500 mg kg−1 body weight; n= 6). B, Nampt mRNA concentrations and C) Nampt protein abundance were assessed 8 h after AICAR treatment (500 mg kg−1 body weight; n= 10–13). * Indicates vs. saline (P < 0.05); † indicates vs. 2 and 4 h (P < 0.05); # indicates vs. WT (P < 0.05).
