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Each rat received a primed (10 mg kg−1) continuous (9.6 mg kg−1 h−1) i.v. infusion of ranolazine or the same volume of saline for 120 min. CEU measurements were made before and at 30, 60 and 120 min after the initiation of ranolazine infusion. A, MBV; B, MFV; C, MBF; D, MAP. n= 5 each. *P < 0.05 vs. control.
