Figure 8. Ranolazine causes arterial vasodilatation on arteries pre-constricted with phenylephrine but not high potassium.

A and B, effects of ranolazine (3 μm) on isolated distal saphenous artery pre-constricted with phenylephrine (2 μm) and representative tomographic images. C and D, effects of ranolazine (3 μm) on isolated distal saphenous artery pre-constricted with potassium (60 mm) and representative tomographic images. n= 6 per group. *P < 0.01 vs. control, **P= 0.014 endothelium denuded vs. endothelium intact arteries.