Table III.
Risk of EAC as estimated by mtDNA copy number
| MtDNA copy number | Cases, N (%) | Controls, N (%) | Adjusted ORa | P |
|---|---|---|---|---|
| By median | ||||
| ≥1.22 | 83 (38.07) | 109 (50.00) | 1 (reference) | |
| <1.22 | 135 (61.93) | 109 (50.00) | 1.55 (1.05–2.29) | 0.028 |
| By quartile | ||||
| ≥1.39 | 43 (19.72) | 54 (24.77) | 1 (reference) | |
| 1.22–1.39 | 40 (18.35) | 55 (25.23) | 0.88 (0.49–1.59) | 0.691 |
| 1.03–1.22 | 52 (23.85) | 54 (24.77) | 1.14 (0.65–2.02) | 0.650 |
| <1.03 | 83 (38.07) | 55 (25.23) | 1.77 (1.03–3.04) | 0.038 |
| P for trend | 0.017 | |||
aAdjusted for age, sex, ethnicity and smoking status.