Table IV.

Association of EAC with mtDNA copy number stratified by selected host characteristics

Host characteristics	Cases, N (%)	Controls, N (%)	Adjusted OR (95% CI)a	P
Sex
Male
>1.22	57 (32.95)	84 (48.55)	1 (reference)
≤1.22	116 (67.05)	89 (51.45)	1.85 (1.19–2.88)	0.006
Female
>1.22	26 (57.78)	25 (55.56)	1 (reference)
≤1.22	19 (42.22)	20 (44.44)	0.86 (0.35–2.15)	0.750
Age, years
Age ≤ 60
>1.22	39 (38.61)	56 (51.85)	1 (reference)
≤1.22	62 (61.39)	52 (48.15)	1.89 (1.06–3.38)	0.031
Age > 60
>1.22	44 (37.61)	53 (48.18)	1 (reference)
≤1.22	73 (62.39)	57 (51.82)	1.38 (0.79–2.39)	0.256
Smoking status
Never smoking
>1.22	30 (44.12)	56 (58.33)	1 (reference)
≤1.22	38 (55.88)	40 (41.67)	1.90 (0.98–3.69)	0.058
Ever smoking
>1.22	53 (35.33)	53 (43.44)	1 (reference)
≤1.22	97 (64.67)	69 (56.56)	1.39 (0.85–2.28)	0.192

^aSex: adjusted for age, ethnicity and smoking status; age: adjusted for sex, ethnicity and smoking status; smoking status: adjusted for age, sex and ethnicity.