TABLE 2.

Univariate and multivariable proportional hazards models of risk of overall mortality (survival time measured from date of surgery), 1983–2000

	Univariate models		Multivariable model
Variables	HR (95% CI)	P	HR (95% CI)	P
Age	1.07 (1.05, 1.08)	<0.001	1.04 (1.03, 1.06)	<0.001
Preoperative ED	1.71 (1.34, 2.23)	<0.001	1.25 (0.97, 1.66)	0.111
Year of surgery	0.90 (0.88, 0.92)	<0.001	0.91 (0.89, 0.94)	<0.001
Postoperative GS:
7 vs <7	1.96 (1.60, 2.39)	<0.001	1.50 (1.20, 1.87)	<0.001
8–10 vs <7	3.84 (2.96, 4.97)	<0.001	2.40 (1.80, 3.21)	<0.001
Body mass index
25–30 vs <25	1.07 (0.87, 1.32)	0.50	– –	– –
>30 vs <25	1.16 (0.82, 1.64)	0.41	– –	– –
Postoperative stage
EPE vs OC	1.59 (1.29, 1.98)	<0.001	1.18 (0.94, 1.48)	0.15
SVI vs OC	3.23 (2.34, 4.47)	<0.001	1.72 (1.21, 2.44)	0.003
LN positive vs OC	4.43 (3.32, 5.89)	<0.001	2.54 (1.84, 3.52)	<0.001
Charlson comorbidity index
1 vs 0	1.29 (0.97, 1.73)	0.08	– –	– –
2+ vs 0	0.91 (0.50, 1.66)	0.76	– –	– –

HR, hazard ratio; CI, confidence interval; ED, erectile dysfunction; EPE, extra-prostatic extension; GS, Gleason score; OC, organ confined; SVI, seminal vesicle involvement; LN, lymph nodes; ‘– –’ indicates variables that were not statistically significant in the multivariable model.