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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: J Neuropathol Exp Neurol. 2013 Oct;72(10):10.1097/NEN.0b013e3182a5f96e. doi: 10.1097/NEN.0b013e3182a5f96e

Figure 1.

Figure 1

Age-related declines in neuromuscular performance and muscle strength in Trembler J (TrJ) mice. (A) Longitudinal study of performance on the accelerating Rotarod reveals a main effect of genotype (***p < 0.001 ANOVA, error bars represent SEM) and a significant decline from baseline at 5 months in TrJ mice (#p < 0.05). (B) TrJ mice show impairment in rearing behavior at all 3 ages analyzed (**p < 0.01, Student t-test, error bars represent SEM), and a decrease in the number of rears between 2 and 10 months (# p < 0.05). (C) At 2 months of age there is no significant difference in forepaw grip strength between the genotypes, while at 5 and 10 months, forepaw grip strength is reduced in TrJ mice (*p < 0.05, Student t test). There is no significant change in forelimb grip strength with age in either genotype. n = 5 to 6 mice/genotype/age group.