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The Relative Insulin Sensitivity Index (RISI) [100/√ blood glucose level x insulin level] before (A) and after (B) pioglitazone (PIO) treatment in normal (N) and transgenic mice over-expressing bovine growth hormone (Tg). Values are means ± SEM. a, b – values that do not share the same letter in the superscript are significantly different (p<0.05).
