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. Author manuscript; available in PMC: 2014 Sep 15.
Published in final edited form as: Toxicology. 2013 Jul 10;311(3):10.1016/j.tox.2013.07.002. doi: 10.1016/j.tox.2013.07.002

Fig. 2.

Fig. 2

PPARβ/δ-dependent modulation of hepatic triglyceride accumulation and active SREBP1 after four months of treatment. (A) Average concentration of hepatic triglycerides in control and ethanol-fed Pparβ/δ+/+ and Pparβ/δ−/− mice. (B) Average expression of hepatic mRNA encoding Insig1 in control and ethanol-fed Pparβ/δ+/+ and Pparβ/δ−/− mice. Average triglyceride concentrations and normalized hybridization values represent the mean ± S.E.M.. (C) Western blot analysis of inactive (uncleaved-U) and active (cleaved-C) SREBP1 in the liver of control and ethanol-fed Pparβ/δ+/+ and Pparβ/δ−/− mice. Values with different superscripts are statistically different at P ≤ 0.05.