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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: Vet Clin North Am Small Anim Pract. 2013 Sep;43(5):10.1016/j.cvsm.2013.05.002. doi: 10.1016/j.cvsm.2013.05.002

Figure 4.

Figure 4

Cats are sensitive to the toxic effects of acetaminophen, in part because they glucuronidate acetaminophen less efficiently than humans or dogs. Shown are data from several studies comparing the urinary metabolite profiles of acetaminophen following oral administration of a nontoxic dose of 100 mg / kg to 4 dogs, a toxic dose of 120 mg / kg to 6 cats, a therapeutic dose of 20 mg / kg to healthy human volunteers, and an intentional overdose taken by human patients. Data are from Savides et al (1984) for cat and dog, and Prescott (1980) for human volunteers and overdose patients.