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. Author manuscript; available in PMC: 2014 Oct 10.
Published in final edited form as: Mol Cell. 2013 Sep 26;52(1):10.1016/j.molcel.2013.08.037. doi: 10.1016/j.molcel.2013.08.037

Figure 6. Cell-specific sites observed in primary mouse tissues as well as for the glucocorticoid receptor.

Figure 6

A) ER binding shows a high degree of cell type specificity between mouse liver (red) and uterus (blue). B) The canonical ERE motif was identified using ER binding sites found in either liver or uterus. C) Similar to results in human cancer cell lines, tissue-specific ER binding sites are significantly less likely to harbor EREs than shared sites bound by ER in both liver and uterus. D) Very few GR binding sites are bound in both ECC-1 and A549. E) The distribution of the best sequence match to an GRBE is shown for each ECC-1 specific (blue), A549 specific (yellow) and shared (red) GR binding site. F) Sites without a strong match to a GRBE are more likely to be found in open chromatin prior to treatment with dexamethasone than sites without a strong match to a GRBE. See also Figure S5.