Fig 4.
Mutations in MprF identified in daptomycin-NS S. aureus. MprF consists of an N-terminal flippase domain and a C-terminal phosphatidylglycerol lysylination domain. Mutations have been identified in both domains, as outlined in the following references: a, reference 96; b, reference 101; c, reference 88; d, reference 98; e, reference 103; f, reference 115; g, reference 90; h, reference 201; i, reference 94.