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. 2013 Nov;57(11):5543–5547. doi: 10.1128/AAC.02394-12

Table 1.

5FC antagonism of FLC activity is PDR1 and CDR1 dependent

Strain background Genotype Medium MIC (μg/ml) of:
FLC FLC + 5FCa
66032 Wild type RPMI 16 128
pdr1Δ 8 8
cdr1Δ 4 8
66032 Wild type YPD 16 128
pdr1Δ 4 4
cdr1Δ 2 4
BG2 Wild type YPD 8 128
pdr1Δ 4 8
cdr1Δ 2 4
a

5FC concentrations were subinhibitory at 0.008 and 0.5 μg/ml in RPMI and YPD media, respectively.