Fig 4.
Circulating PA levels in a therapeutic efficacy-based study in rabbits (trigger-based intervention). Geometric mean PA concentrations with standard deviations, as measured by ELISA, in rabbits (n = 32) exposed to 188 ± 43 (mean ± standard deviation) LD50 of B. anthracis Ames strain spores via aerosol inhalation are shown. (A) Nonsurvivors; (B) survivors. Limit of detection (LOD) = 2.0 ng/ml. Values below the LOD were replaced with one-half the LOD (1.0 ng/ml). *, standard deviations below the limit of detection were truncated for plotting purposes.