Official websites use .gov
A
.gov website belongs to an official
government organization in the United States.
Secure .gov websites use HTTPS
A lock (
) or https:// means you've safely
connected to the .gov website. Share sensitive
information only on official, secure websites.
Posaconazole monotherapy dose-response curves for each isolate. Open symbols represent Cyp51 wild-type organisms, and closed symbols represent Cyp51 mutants. Each data point is the mean (± standard deviation [SD]) log10 CE/ml of lung homogenate for four mice. The horizontal dashed line represents net stasis or infectious burden at the start of therapy. Points above the line represent an increase in burden (i.e., net growth), whereas those below the line represent a decrease in burden.
