Concentrations of isavuconazole (BAL4815) in plasma after administration of the oral prodrug (BAL8557) at 640, 160, 40, or 10 mg/kg. Each symbol represents the geometric mean ± standard deviation for three mice. The peak concentration (Cmax), 24-h AUC0-∞ (AUC), and elimination half life (t1/2) are shown for each dose.