Table 1.
Resistance rates of ESBL-producing E. coli isolates by sequence type and ESBL type
| Antimicrobial agent | Rate of resistance (%) by sequence type (no. of isolates) |
P value for sequence typesa | Rate of resistance (%) by ESBL type (no. of isolates) |
P value by ESBL typeb | |||||
|---|---|---|---|---|---|---|---|---|---|
| ST131 (20) | ST648 (19) | ST10 complex (19) | ST38 (16) | Other STs (65) | CTX-M1 group (33) | CTX-M9 group (99) | |||
| Ceftazidime | 30.0 | 26.3 | 15.8 | 6.3 | 29.2 | 0.298 | 69.7 | 6.1 | 0.000 |
| Cefotaxime | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | —b | 100.0 | 100.0 | — |
| Ceftriaxone | 100.0 | 100.0 | 100.0 | 100.0 | 100.0 | — | 100.0 | 100.0 | — |
| Aztreonam | 65.0 | 31.6 | 63.2 | 18.8 | 63.1 | 0.003 | 87.9 | 36.4 | 0.000 |
| Cefoxitin | 0.0 | 5.3 | 5.3 | 12.5 | 7.7 | 0.665 | 18.2 | 2.0 | 0.003 |
| Cefepime | 25.0 | 26.3 | 10.5 | 12.5 | 20.0 | 0.680 | 51.5 | 8.1 | 0.000 |
| Levofloxacin | 75.0 | 100.0 | 68.4 | 18.8 | 55.4 | 0.000 | 75.8 | 51.5 | 0.016 |
| Moxifloxacin | 75.0 | 100.0 | 68.4 | 18.8 | 58.5 | 0.000 | 75.8 | 54.5 | 0.040 |
| Piperacillin-tazobactam | 0.0 | 0.0 | 5.3 | 6.3 | 0.0 | 0.131 | 0.0 | 2.0 | 1.000 |
| Cefoperazone-sulbactam | 30.0 | 26.3 | 5.3 | 18.8 | 10.8 | 0.099 | 3.0 | 18.2 | 0.042 |
| Ciprofloxacin | 75.0 | 100.0 | 68.4 | 18.8 | 55.4 | 0.000 | 72.7 | 57.6 | 0.150 |
| Amikacin | 0.0 | 0.0 | 10.5 | 0.0 | 6.2 | 0.400 | 3.0 | 4.0 | 1.000 |
a
P values of <0.01, indicating significant differences, are shown in boldface. —, no P value calculated, since the data did not meet the criteria of the Fisher exact t test.
b
For 7 subgroups of the CTX-M-1 and CTX-M-9 groups, P values were not calculated due to the small number of strains.