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Effect of COBI and RTV on the accumulation of TFV in freshly isolated RPTECs (A) and human renal cortical slices (B). The results represent means ± SD from 4 independent measurements in RPTECs from two separate donors and 3 independent measurements in renal cortical tissue. Probenecid (PBC; 200 μM) was used as a control inhibitor of the active uptake of TFV.
