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. 2013 Oct;57(10):4990–4998. doi: 10.1128/AAC.01161-13

Fig 2.

Fig 2

Homology model of Pneumocystis jirovecii DHFR (green), with NADPH (yellow) and trimethoprim (cyan). The locations of the 22 individual sites where amino acid substitutions have been observed in clinical samples (26) are indicated in violet and by the residue number.