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Susceptibility of baseline sample-derived NS5B chimeric replicons to deleobuvir and interferon alfa
| Parameter | Deleobuvir EC50 (nM) |
IFN-α EC50 (IU/ml) |
||
|---|---|---|---|---|
| GT1a (n = 30) | GT1b (n = 40) | GT1a (n = 30) | GT1b (n = 40) | |
| Range | 1.2–153 | 0.4–98 | 0.12–0.38 | 0.13–0.3 |
| Geometric mean | 26 | 7.2 | 0.19 | 0.19 |
