Table 2.
Substitutions identified in the genome of CVB3 mutants resistant to compound 1
| Serial passage no. | Amino acid substitution(s) within: |
||||
|---|---|---|---|---|---|
| VP1 | 2A | 2C | 3A | 3D | |
| 1 | N2D | H57Y | |||
| H44R | |||||
| 2 | D152E | N2D | H57Y | ||
| S109I | |||||
| 3 | E77Q | N2D | I54F | P336S | |
| V40A | |||||
| A95V | |||||
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