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Overview of the Leloir pathway (A) and GNB/LNB pathway (B) in Bifidobacterium bifidum. LNBP, NahK, GalT2, and GalE2 are encoded in the same gene cluster (4). In contrast, the classic Leloir pathway (A) is encoded by scattered genes, and evidence is lacking for the existence of metabolic crossover between both pathways. Gene locus tags of the corresponding enzymes are listed in Table 1.
