Phylogenies of representative sets of cyanobacteria, based on RubisCO large-subunit proteins (RbcL and CbbL proteins). Phylogenies were constructed as detailed previously (40). Note that oceanic cyanobacteria, i.e., α-cyanobacteria (Prochlorococcus and Synechococcus species), have form 1A RubisCO enzymes, fall into two minor groups, and are readily distinguished from the more diverse β-cyanobacterial group (form 1B RubisCO).