Molecular modeling of the Mgm101 core domain (from A115 to V237) based on the Rad52 structure (1H2I). (A) The positions of N150, F153, and F235, which are highly conserved in Rad52-related proteins, are highlighted. Also indicated are C216 and C217, which form a putative redox sensor for regulating Mgm101 function. (B) Surface representation model of a 14-mer ring formed by Mgm101115-237. (Adapted from reference 165 [© The American Society for Biochemistry and Molecular Biology].)