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. 2013 Sep;77(3):440–475. doi: 10.1128/MMBR.00018-13

Fig 7.

Fig 7

TFRs share nine conserved α helices. In the front view, the DNA-binding domain is made up of helices 1 to 3. In the side view, helices 5 to 7 in the ligand-binding domain form a central triangle. In the top view, helices 8 and 9 from each monomer form a four-helical bundle that makes up the dimer interface. The structure of Rha06780 (PDB ID 2NX4) is shown, as it shows a structure typical of TFRs (24).