Table 1.

Characteristics of patients infected and/or colonized with the ertapenem-resistant, CTX-M-15-producing, and porin-deficient clonal K. pneumoniae isolates

Patient no.	Age (yr)/gender	Admission date	Days in the unit prior to colonization	Days in the unit prior to infection	Source of carriage	Type of infection	Reason for ICU admission	Underlying disease(s)	Antibiotic regimen prior to infectionc	Antibiotic regimen for infectionc	Outcome
1	69/M	4/27/12		27		Bacteremia	Respiratory failure	Diabetes mellitus/tetraplegia	FEP	MEM, CST	Deathb
2	80/F	5/6/12	23		Fecal		Stroke	Pulmonary fibrosis	TZP, FEP		Death
3	75/F	5/15/12	14		Fecal, bronchial		Stroke/respiratory failure		TZP		Death
4	75/F	5/16/12	13		Fecal		Stroke/septic shock	Hypothyroidism	VAN		Death
5a	39/Ma	5/18/12		4		Pneumonia	Stroke/pneumonia	Pulmonary fibrosis/diabetes mellitus/morbid obesity	TZP	MEM, CST	Discharged
6	77/M	6/1/12	10		Fecal		Polytrauma	Chronic lymphocytic leukemia	FEP, MTZ		Discharged
7	57/M	6/6/12	6	19	Fecal	Bacteremia	Stroke	Diabetes mellitus/alcoholic cirrhosis	TZP	MEM	Discharged
8	76/M	6/7/12	5		Fecal		Stroke		FEP		Discharged
9	60/M	6/17/12	15		Fecal		Respiratory failure	Guillain-Barré syndrome	TZP		Death
10	37/F	6/27/12	5		Fecal		Heart failure	Diabetes mellitus			Discharged
11	50/M	7/13/12	14	23	Fecal	Pneumonia	Polytrauma	Alcoholic cirrhosis	FEP	MEM, CST	Discharged
12	56/F	7/20/12	12	14	Fecal bronchial	Bacteremia	Status epilepticus	Diabetes mellitus/alcoholic cirrhosis/hypothyroidism	CST	MEM	Deathb
13	79/M	7/23/12	14		Fecal, bronchial		Cerebral hemorrhage		FEP		Death
14	87/F	8/2/12	4		Fecal		Stroke/renal failure		TZP		Death
15	61/M	8/23/12	3		Fecal		Heart failure		SAM		Discharged
16	72/M	9/16/12	10	12	Fecal	Pneumonia	Stroke		FEP	MEM	Discharged
17	62/M	9/16/2	12		Bronchial		Stroke	Diabetes mellitus	AZM		Discharged
18	79/F	9/25/12		7		Bacteremia	Abdominal surgery		TIM, AMK, MTZ	MEM, CST	Deathb
19	18/M	10/26/12	11		Fecal		Polytrauma	Hypothyroidism	CAZ		Discharged

^aIndex case.

^bDue to infection.

^cAMK, amikacin; AZM, azithromycin; CAZ, ceftazidime; CST, colistin; FEP, cefepime; MEM, meropenem; MTZ, metronidazole; SAM, ampicillin-sulbactam; TZP, piperacillin-tazobactam; TIM, ticarcillin-clavulanic acid; VAN, vancomycin.