Table 2.

Summary of the most-frequent mutations associated with resistance to INH, RIF, and streptomycin^a

Drug	Mutation	No. of isolates
Isoniazid	KatG S315T/G	47
	InhA C−15T	13
	Other	11
	Total	66b
Rifampin	RpoB S531L	52
	RpoB H526D/Y	9
	RpoB D516F/V	4
	Other	1
	Total	66
Streptomycin	rrs C517T	30
	rrs A514C	1
	RpsL K43R	4
	RpsL K88R	1
	Other	11
	Total	47

^aThe conventional Escherichia coli numbering system is used for mutation positions in RpoB and rrs.

^bThere was some overlap in isoniazid resistance mutations.