Deletion of Cdc42 has no effect on EC proliferation in vivo. (A through F) Sections from E9.5 control (A, C, and E) and CEKO (B, D, and F) embryos were stained with antibodies against pH3 (A and B) and PECAM-1 (C and D). The numbers of pH3 and PECAM-1 double-positive cells in control (E) and CEKO (F) embryos are comparable. Bars, 25 μm.