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. 2013 Nov;33(21):4225–4240. doi: 10.1128/MCB.00856-13

Fig 9.

Fig 9

Abnormal collagen organization in TM tissue from Postn-deficient (Postn−/−) mice. (A) Postn+/+ TM tissue contained normal collagen fibrils (bottom left, asterisk). In contrast, TM tissues from Postn−/− mice showed large empty spaces indicative of defective collagen organization (bottom right, asterisk) (n = 5). Scale bar, 2 μm. Five sectors per eye were evaluated. Postn deficiency did not affect the collagens in sclera (S). (B) Quantitative assessment of the amount of collagens occupying the spaces in the trabecular beams (∗∗, P = 0.0063) (n = 4). (C) Severity grades of abnormal collagen fibers in Postn+/+ and Postn−/− TM tissues (P = 0.0004) (n = 4). (D) Severity grades of abnormal TM cell morphology in Postn+/+ and Postn−/− TM tissues (P = 0.0011) (n = 4).