Table 1.
A tatC mutant is attenuated in mice.
| Genotype a | Route of Inoculation | Organ b | Median CI c | Number of mice | P value d |
|---|---|---|---|---|---|
| tatC | oral | small intestine | 0.0065 | 11 | <0.0005 |
| oral | spleen | 0.0077 | 16 | <0.0005 | |
| i.p. | spleen | 0.0045 | 5 | <0.0005 |
a
Strains used were JS135 and JS1195 for oral infections, and 14028 and JS1194 for i.p. infections.
b
The entire small intestine was dissected and homogenized.
c
The competitive index (CI) was calculated as described in the experimental procedures.
d
The student’s t test was used to compare the output and the inoculums.