Table 5.
Competition assays with mutants impaired in septation.
| Strain A a | Strain B a | Route of Inoculation | Organ | Median CI b | Number of Mice | P value c |
|---|---|---|---|---|---|---|
| amiA amiC sufI | WT | i.p. | spleen | 0.016 | 5 | 0.0029 |
| amiA amiC sufI tatC | amiA amiC sufI | i.p. | spleen | 0.26 | 9 | 0.036 |
| oral | spleen | 0.32 | 9 | 0.033 | ||
| small intestine | 1.30 | 9 | NS | |||
| amiA amiC sufI +amiA+ | WT | i.p. | spleen | 1.49 | 8 | NS |
| amiA amiC sufI +amiC+ | WT | i.p. | spleen | 0.36 | 8 | 0.034 |
| amiA amiC sufI +sufI+ | WT | i.p. | spleen | 0.47 | 8 | NS |
| +amiA+ | WT | i.p. | spleen | 1.09 | 5 | NS |
| +amiC+ | WT | i.p. | spleen | 1.02 | 10 | NS |
| +sufI+ | WT | i.p. | spleen | 0.96 | 5 | NS |
a
The strains used were 14028, JS2019, JS2020, JS2034, JS2035, JS2036, JS2031, JS2032, and JS2033 for i.p. infections, and JS2019 and JS2020 for oral infections.
b
The competitive index (CI) was calculated as described in the experimental procedures.
c
The student’s t test was used to compare the output and the inoculums.