Table 6.
Competition assays with SPI1 mutants.
| Strain A a | Strain B a | Median CI b | Number of Mice | P value c |
|---|---|---|---|---|
| Δspi1 | wt | 0.015 | 7 | <0.005 |
| ΔtatC Δspi1 | Δspi1 | 0.016 | 8 | <0.005 |
| ΔamiAC ΔsufI Δspi1 | Δspi1 | 0.0065 | 5 | <0.005 |
a
The strains used were JS135, JS2028, JS2029, and JS2030. Mice were infected orally with 109 bacteria/mouse. Bacteria were recovered from the distal portion of the small intestine.
b
The competitive index (CI) was calculated as described in the experimental procedures.
c
The student’s t test was used to compare the output and the inoculums. NS, not significant.