Fig. 7.
(A) Mean number of retrogradely labeled DRN cells per section per rat according to rostrocaudal position for the various populations of projection neurons. (B) Cumulative (left axis) and mean ± SEM (right axis) counts of retrogradely labeled neurons projecting to each possible combination of terminal fields from all animals (n = 9). (C) Distance to the median section, last section which contained retrogradely labeled neurons, and the end of the nucleus ± SEM for the three populations of singly-projecting neurons. Note that roughly one-third to one-quarter of the nucleus, i.e. the caudal tail, is devoid of retrograde labeling. OFC projection cells in DRN cluster significantly more rostrally than do mPFC projection cells (p<0.05). DRN, dorsal raphe nucleus; 5HT, serotonin; OFC, orbitofrontal cortex; mPFC, medial prefrontal cortex; ACC, anterior cingulate cortex.