Table 2. Variables significantly different by paired t-test pre vs. post intervention at α ≤ 0.0002 (adjusted for multiple comparisons).

Metabolite	Mean Pre	SD Pre	Mean Post	SD Post	P-value
Metabolites that increased post supplementation
PC22:6n3 (nmol/g)	127	34.7	215	36.6	< 0.0001
PC20:5n3 (nmol/g)	32.8	19.9	182.2	53.9	< 0.0001
CE20:5n3 (nmol/g)	27.0	17.8	152.1	59.3	< 0.0001
TG22:6n3 (nmol/g)	13.5	6.63	69.6	26.5	< 0.0001
TG22:5n3 (nmol/g)	8.18	2.50	21.8	9.85	0.0001
TG20:5n3 (nmol/g)	4.87	3.53	50.4	21.0	< 0.0001
PE20:5n3 (nmol/g)	4.44	2.34	22.8	9.25	< 0.0001
LY20:5n3 (nmol/g)	0.588	0.413	3.28	1.42	< 0.0001
17,18-DiHETE (nmol/L)	0.476	0.155	2.68	1.35	< 0.0001
5-oxo-ETE (nmol/L)	0.458	0.122	3.46	1.91	< 0.0001
16,17-DiHDPE (nmol/L)	0.245	0.075	0.492	0.170	0.0002
10(11)-EpDPE (nmol/L)	0.162	0.094	0.548	0.271	< 0.0001
8,9-DiHETE (nmol/L)	0.069	0.031	0.457	0.223	< 0.0001
14,15-DiHETE (nmol/L)	0.060	0.027	0.413	0.221	< 0.0001
16(17)-EpDPE (nmol/L)	0.056	0.046	0.222	0.121	0.0001
11,12-DiHETE (nmol/L)	0.040	0.022	0.243	0.115	< 0.0001
Metabolites that decreased post supplementation
PC18:2n6 (nmol/g)	958.54	212.13	779.99	206.65	0.0002
CE18:3n6 (nmol/g)	25.6	12.6	13.2	7.28	0.0001
PC22:4n6 (nmol/g)	12.0	2.54	6.95	2.15	< 0.0001
PE20:3n6 (nmol/g)	8.59	2.91	5.32	2.45	< 0.0001
PC22:5n6 (nmol/g)	8.49	3.43	3.86	1.52	< 0.0001