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. 2013 Oct 24;8(10):e77419. doi: 10.1371/journal.pone.0077419

Figure 5. Gene and protein expression: ARNT and cyclinD2.

Figure 5

(A) Gene expression in β-ARNT islets (white bars) expressed as percentage of gene expression in floxed control islets (black bars) (n = 13 β-ARNT and 13 FC). ***p<0.001, **p<0.01, *p<0.05, Ŧ p = 0.06, Δ p = 0.08, t-test. Bars represent mean±SEM. (B) Western blot of ARNT in islets from non pregnant and pregnant wild type females (top) Western blot of cyclinD2 in islets from non pregnant and pregnant floxed control and β-ARNT females (bottom). (C) Quantitation of ARNT protein in wild type female islets, expressed as fold change of non pregnant islets (n = 6 vs. 6). *p = 0.048, t-test. Bars represent mean±SEM. (D) Quantitation of cyclinD2 protein in non pregnant and pregnant β-ARNT (white bars) and floxed control (black bars) islets, expressed as fold change of non pregnant floxed control islets (n = 4 vs. 4). *p = 0.02, **p = 0.002, t-test. Bars represent mean±SEM.