Table 2. Demographic, clinical and anthropometric characteristics of 1179* adult patients with pulmonary tuberculosis who were treated at JSS (2004-2009), stratified by outcomes**.
| Characteristic | Treatment success # N=756 | TB death § N=60 | Default // during TB treatment N=354 | P values (Treatment success vs. TB death) | P values (Treatment success vs. default) |
|---|---|---|---|---|---|
| DEMOGRAPHIC & GEOGRAPHIC | |||||
| Median age in years, (IQR) | 35 (27,45) | 40 (35,53) | 40 (29,52) | P=0.0002† | P=0.0001† |
| Gender, (%) | |||||
| Men | 479 (63) | 46 (77) | 251 (71) | P=0.05‡ | P=0.02‡ |
| Women | 277 (37) | 14 (23) | 103 (29) | ||
| Residence, (%) | |||||
| Rural | 722 (96) | 54 (90) | 327 (92) | P=0.07‡ | P=0.05‡ |
| Urban | 34 (4) | 6 (10) | 27 (8) | ||
| Location of residence, (%) | |||||
| Group 1: related to village health program/outreach clinic | 140 (18) | 11(18) | 34 (10) | P=0.27‡ | P<0.0005‡ |
| Group 2 <20 km from hospital | 87 (12) | 11 (18) | 32 (9) | ||
| Group 3: >20 km from hospital | 529 (70) | 38 (64) | 288 (81) | ||
| DISEASE RELATED | |||||
| Sputum smear, (%) | |||||
| Smear positive | 499 (66) | 37 (62) | 215 (61) | P=0.48‡ | P=0.09‡ |
| Smear negative | 257 (34) | 23 (38) | 139 (39) | ||
| Sputum grade, (%) | |||||
| 1+ | 156 (31) | 10 (27) | 60 (28) | P=0.16‡ | P=0.31‡ |
| 2+ | 151 (30) | 7 (19) | 59 (27) | ||
| 3+ | 192 (39) | 20 (46) | 96 (45) | ||
| Treatment history, (%) | |||||
| New cases | 628 (83) | 46 (77) | 269 (76) | P=0.22‡ | P=0.007‡ |
| Retreatment cases | 128 (17) | 14 (23) | 85 (24) | ||
| CO-MORBIDITIES | |||||
| No. of patients with HIV co-infection, % | 9 (23) | 10 (26) | 20 (51) | P<0.0005‡ | P<0.0005‡ |
| ANTHROPOMETRIC DATA | |||||
| Weight at diagnosis[Median (IQR)] | |||||
| Men | [n=478]42.5 (37.8,47.3) | [n=46]38.5 (34.4,44.6) | [n=245]41.7 (37.1,47.5) | P=0.002† | P=0.35† |
| Women | [n=277]34.3 (30.4,38.8)(30.4,38.8)(30.4,38.8) | [n=14]32.7 (29,38.1) | [n=100]33.9 (30,37.3) | P=0.46† | P=0.24† |
| BMI at diagnosis [median(IQR)] | |||||
| Men | [N=459]16.1 (14.7,17.5) | [N=46]15.0 (12.7,16.4) | [n=219]15.8 (14.4,17.4) | P=0.0002† | P=0.27† |
| Women | [N=269]15.1 (13.7,16.8) | [n=14]14.6 (12.8,17.8) | [N=83]14.7 (13.4,16) | P=0.65† | P=0.05† |
*Excludes 5 patients with unknown outcomes & 4 patients with treatment failure. ** 516 patients who were “transferred out” to the RNTCP &did not have their treatment outcomes recorded have been excluded in this analysis. ‡ Fisher exact test. † Mann-Whitney test. # this includes patients who were cured and those who completed treatment. § Death due to any reason occurring during treatment of TB. // Interruption of therapy for 2 consecutive months or more.