Table 3. Overview of mutations in A niger tupA mutants.
| Strain | Allel | Position of mutation inORF (including introns) | Consequence of the mutation (s) | Protein sequence(WT: 1–590) | |
| RD6.47#28 | tupA-1 | GA deletion (61, 62) | out of frame after aa 21 | truncation | 1–21 |
| RD6.13#22 | tupA-2 | TA to AT (1561, 1562) | ATT to ATA (silent I remains I);AAG to TAG (K to stop) | truncation | 1–358 |
| RD6.13#53 | tupA-3 | A to C (487) | mutation in 3′ intron splice siteTAG to TCG | truncation | 1–60 |
| RD15.4#2 | tupA-4 | G to C (2351) | TGG to TCG (W to S) | point mutation | 1–590 (W to S at 575) |
| RD15.4#3 | tupA-5 | G to A (889) | mutation in 3′ intron splice siteCAG to CAA | truncation | 1–170 |
| RD15.4#24 | tupA-6 | extra T (1355) | Out of frame after aa 316 | truncation | 1–316 |
| RD15.4#26 | tupA-7 | extra T (786) | Out of frame after aa 160 | truncation | 1–160 |
| RD15.4#27 | tupA-8 | C to T (2128) | TCT to TTT (S to F) | point mutation | 1–590 (S to F at 489) |
| RD15.4#29 | tupA-9 | A to T (1772) | AAG to TAG (K to stop) | truncation | 1–473 |
| RD15.4#37 | tupA-10 | C to T and C deletion(669, 670) | GGC to GGT (Silent G remains G);out of frame after aa 122 | truncation | 1–122 |
| RD15.4#47 | tupA-11 | TG to GA (1664, 1665) | TGG to GAT (W to D) | point mutation | 1–590 (W to D at 393) |
| RD15.4#49 | tupA-12 | C to T (43) | CAA to TAA (Q to stop) | truncation | 1–14 |
| RD15.4#52 | tupA-13 | T to C (2350) | TTG to CCG (W to R) | point mutation | 1–590 W to R at 575) |
| RD15.4#60 | tupA-14 | no PCR product obtained | |||
| RD15.8#13 | tupA-15 | C to T (1856) | TCG to TTG (S to L) | point mutation | 1–590 (S to L at 457) |
| RD15.8#27 | tupA-16 | G to A (2125) | GGT to GAT (G to D) | point mutation | 1–590 (G to D at 488) |
| RD15.8#36 | tupA-17 | G to A (2144) | TGG to TGA (W to stop) | truncation | 1–519 |