Table 1. Pyruvate dehydrogenase complex enzyme decomposition in structural domain according to scop fold classification.
Gene name/enzyme | structural domain | domain function | label in the |
(scop) | Fig. 1 & 2 & 3 | ||
PdhA/enzyme 1 | c.36.1 | Binding TPP and active site (first reaction) | PdhA |
PdhB/enzyme 1 | c.36.1 | Binding TPP and active site (second reaction) | PdhB1 |
c.48.1 | regulatory binding site | PdhB2 | |
PdhC/enzyme 2 | b.84.1 | Lipoyl binding | PdhC1 |
a.9.1 | E1/E3 binding | PdhC2 | |
c.43.1 | Active site | PdhC3 | |
PdhD/enzyme 3 | c.3.1 | Binding FAD | PdhD1 |
c.4.1 | Binding NAD/FAD | PdhD2 | |
d.87.1 | Active site | PdhD3 |