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. 2013 Oct 29;8(10):e77591. doi: 10.1371/journal.pone.0077591

Figure 6. Effect of Adv-hVEGF-hIL-1Ra transduced hBMSCs on the outcome of human islet transplantation.

Figure 6

(A, B, C) The blood glucose level of every mouse after receiving 2000 human islet equivalent transplanted either alone or hBMSCs before or after transduction with Adv-hVEGF-hIL-1Ra (A–C). (D) Diabetes reversal ratio of the diabetic mice after human islet transplantation. Blood glucose ≤250 mg/dl (dashed line) was identified as reversed-diabetes (dashed line in A, B, C). Black triangles indicate mice receiving islets with Adv-hVEGF-hIL-1Ra transduced hBMSCs; gray squares indicate mice receiving islets with hBMSCs; black diamond’s indicate mice receiving islets only.